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In the modern review, we documented the identification as well as characterization of a different atypical opioid receptor with one of a kind adverse regulatory Houses toward opioid peptides.1 Our results confirmed that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can be a broad-spectrum scavenger
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